Systematic review of the impact of cannabinoids on neurobehavioral outcomes in preclinical models of traumatic and nontraumatic spinal cord injury

HIGHLIGHTS

  • who: Faheem I. Bhatti from the Eligibility criteria The inclusion and exclusion criteria used in this review are presented in full in the Supplementary MaterialPopulation and injury model. This review included only preclinical animal models, and human studies were excluded. SCI models such as traumatic injury, spinal cord ischaemia or cryogenic spinal cord injury were included. Peripheral nerve injury or traumatic brain injury models were excluded. Intervention and comparison. Studies were included if they used cannabinoid receptor agonists (e_g WIN, ), cannabinoid receptor antagonists (e_g , or AM630) or endocannabinoid system modulators (e_g acetaminophen or naloxone), administered intravenously, intraperitoneally . . .

     

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