Systemic absorption of triamcinolone acetonide is increased from intrasynovial versus extrasynovial sites and induces hyperglycemia, hyperinsulinemia, and suppression of the hypothalamic-pituitary-adrenal axis

HIGHLIGHTS

• What: To begin to understand the individual case factors that put horses at risk for steroid-induced laminitis, this study aimed to evaluate variations in triamcinolone absorption when injected at an Frontiers in Veterinary Science The authors demonstrated differences in triamcinolone absorption between intra- and extrasynovial injection sites and added to the body of literature investigating the impact of corticosteroid administration on downstream metabolic parameters. This study had several limitations, the first of which is that horses were unable to serve as their own controls due to the extended washout period that would be necessary before repeat . . .
  

   

  

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