Systemic bis-phosphinic acid derivative restores chloride transport in cystic fibrosis mice

HIGHLIGHTS

• who: Mu00e9lanie Faria da Cunha from the Department have published the research work: Systemic bis-phosphinic acid derivative restores chloride transport in Cystic Fibrosis mice, in the Journal: Scientific Reports Scientific Reports of 28/02/2022
• what: The authors provide in_vivo evidence that the c407 CFTR corrector induces a functional restoration of CFTR in the nasal epithelium of F508del mice after systemic short and long term administration.
• how: For this latter mode of administration the authors used an osmotic pump (Alzet micro-osmotic pump Model 1002) surgically installed subcutaneously in the back of . . .
  

   

  

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