Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice

HIGHLIGHTS

• who: William J. Mason from the DivisionUniversity of have published the article: Systemic gene therapy with thymosin u03b24 alleviates glomerular injury in mice, in the Journal: Scientific Reports Scientific Reports
• what: The authors have shown that ADR injury results in reduced Tmsb4x mRNA levels in glomeruli and particularly in podocytes.
• how: For comparisons of two groups data were analysed using a t test.

SUMMARY

ADR, a chemotherapeutic drug, replicates some of the features of human focal segmental glomerulosclerosis (FSGS)33 and has toxic effects on podocytes in_vitro and in_vivo . . .

 



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