Systemic kappa opioid receptor antagonism accelerates reinforcement learning via augmentation of novelty processing in male mice

HIGHLIGHTS

  • who: Zahra Z. Farahbakhsh from the Subjects Adult, male C BL/ J mice were used for all experiments (Jackson Laboratory, Bar Harbor, ME)Mice were group-housed (, per cage) in a reverse, hour light-dark cycle room. Water was available ad libitum and, .8, g of chow per mouse (Labdiet L D) was provided daily, sufficient to maintain mice at healthy adult weights throughout the course of experiments (20, g bodyweight). All experiments involving the use of mice were in accordance with NIH guidelines and approved by the Vanderbilt University Institutional Animal Care and Use Committee. have . . .

     

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