Systems biology computational modelling of ly303511 and trail-induced apoptosis suggests dynamic regulation of cflip

HIGHLIGHTS

• who: BIOINFORMATICS et al. from the National University of, Department of Physiology, National University of, Stony Brook, NY, USA have published the research: Systems biology Computational modelling of LY303511 and TRAIL-induced apoptosis suggests dynamic regulation of cFLIP, in the Journal: (JOURNAL) of May/28,/2012
• what: The authors had expected LY30 to increase caspase-8 activity, but this experiment showed unexpected transient behaviours, with LY30 causing a significant decrease in caspase-8 activity at 2 h.
• how: Treatments for supplementary experiments are described in Supplementary Material 4.1. The authors made several . . .
  

   

  

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