Systems biology of autophagy in leishmanial infection and its diverse role in precision medicine

HIGHLIGHTS

  • who: April et al. from the QEH, Hong Kong SAR, China University of Manitoba, Canada have published the research work: Systems biology of autophagy in leishmanial infection and its diverse role in precision medicine, in the Journal: (JOURNAL)
  • what: The authors demonstrate the significance of computational approaches in studying autophagy in leishmaniasis.
  • how: The results showed that VAMP8 is important for LC3-associated phagocytosis while GP63 is necessary for L major survival.
  • future: Both autophagy and lipid metabolism are necessary for creation of new perspectives on the investigation of leishmanial therapy . . .

     

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