Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs

HIGHLIGHTS

  • who: Paula Saavedra-Garcu00edaa and collaborators from the College London, London , NN, United KingdomThe University have published the paper: Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs, in the Journal: PNAS | 3 of 12 https://doi.org/10.1073/pnas [2018229118]. of May/12,/2021
  • what: The authors demonstrate that recovering cells are more vulnerable to specific insults than acutely stressed cells and identify the general control nonderepressable 2 (GCN2)-driven cellular response to amino acid scarcity as a key recovery-associated vulnerability. Working toward understanding the stress . . .

     

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