T-bet drives the conversion of human type 3 innate lymphoid cells into functional nk cells

HIGHLIGHTS

• who: Laura Kiekens from the Institute (CCRI), Austria The University of Melbourne, Australia have published the paper: T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells, in the Journal: (JOURNAL)
• what: The authors investigate ILC3NK cell plasticity in mature ILC3s with either ectopic T-BET or EOMES overexpression. The CD94+ cells transdifferentiated from mature ILC3s in this study are not ILC1s, but are characterized as genuine NK cells.
• how: Cells were acquired using the LSRII flow cytometer (BD Biosciences) and data were analyzed with FlowJo_V10.8 . . .
  

   

  

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