T-cell progenitors as a new immunotherapy to bypass hurdles of allogeneic hematopoietic stem cell transplantation

HIGHLIGHTS

  • who: Pierre Gaudeaux from the (IRCCS), Italy University of Birmingham have published the article: T-Cell Progenitors As A New Immunotherapy to Bypass Hurdles of Allogeneic Hematopoietic Stem Cell Transplantation, in the Journal: (JOURNAL)
  • how: This culture process can be applied to all sources of HSC (such as umbilical cord blood and blood of mobilized donors) .

SUMMARY

    Allogeneic hematopoietic stem_cell transplantation (allo-HSCT) is the only available cure for many hematopoietic malignancies and several non-malignant conditions. Before giving rise to fully mature CD4+ or CD8+ singlepositive T_cells (SPs), thymocytes undergo . . .

     

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