T cell specific bob.1/obf.1 expression promotes germinal center response and t helper cell differentiation

HIGHLIGHTS

  • who: Annika C. Betzler from the Department of Oto-Rhino-Laryngology, Ulm University Medical Center, Ulm, Germany, Department of Physiological have published the research work: T Cell Specific BOB.1/OBF.1 Expression Promotes Germinal Center Response and T Helper Cell Differentiation, in the Journal: (JOURNAL)
  • what: Contrary to previous assumptions, the authors provide evidence that the impaired GC reaction described for conventional BOB.1/OBF.1deficient mice cannot exclusively be traced back to the B cell compartment, since BOB.1/OBF.1 deletion in CD4+ T as well as TFH cells also resulted in . . .

     

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