HIGHLIGHTS
- who: Antonella Viola from the Department of Biomedical Sciences, University of Padua, Padua, Italy, Venetian Institute of Molecular Medicine (VIMM) have published the research: T Cells and Cancer: How Metabolism Shapes Immunity, in the Journal: (JOURNAL)
SUMMARY
The paucity of appropriate nutrients represents, so far, a limiting step for the effectiveness of antitumor immune_responses since T_cells infiltrating malignant tissues need to face the tumor hostile environment to exert their functions. Recent findings showed that the selective deletion of AMPK in T_cells decreases IFNγ and Granzyme B production in intratumoral CD8+ T_cells. In main . . .
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