T22-pe24-h6 nanotoxin selectively kills cxcr4-high expressing aml patient cells in vitro and potently blocks dissemination in vivo

HIGHLIGHTS

  • who: Yu00e1iza Nu00fau00f1ez and collaborators from the Institut d`Investigaciu00f3 Biomu00e8dica Sant Pau (IIB SANT PAU), Barcelona, Spain have published the article: T22-PE24-H6 Nanotoxin Selectively Kills CXCR4-High Expressing AML Patient Cells In Vitro and Potently Blocks Dissemination In Vivo, in the Journal: Pharmaceutics 2023, 727 of 31/01/2023
  • what: The aim of this study is to determine the antineoplastic effect of the nanoparticle T22-PE24-H6 in AML. The authors report that T22-PE24-H6 has the potential to selectively eliminate CXCR4+ AML human cells through the induction of apoptotic death . . .

     

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