Tafa4 reverses mechanical allodynia through activation of gabaergic transmission and microglial process retraction

HIGHLIGHTS

• who: Charline Kambrun from the InstitutUniversity Bordeaux, UMR, Bordeaux, France have published the research: TAFA4 Reverses Mechanical Allodynia through Activation of GABAergic Transmission and Microglial Process Retraction, in the Journal: (JOURNAL) of March/13,/2018
• what: The authors show that the C-LTMR-derived chemokine induces a reinforcement of inhibitory synaptic transmission within spinal networks which consequently depresses local excitatory synapses and impairs synaptic transmission from high-threshold C-fibers. animals with inflammation induced by Freund's complete adjuvant decreases the noxious stimulus-induced neuronal responses recorded vivo and alleviates pain. The authors used the . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.