Tak-071, a muscarinic m1 receptor positive allosteric modulator, attenuates scopolamine-induced quantitative electroencephalogram power spectral changes in cynomolgus monkeys

HIGHLIGHTS

• who: Emi Kurimoto et al. from the Kanagawa, JapanEditor: Kiyoshi Nakahara, Kochi University of have published the article: TAK-071, a muscarinic M1 receptor positive allosteric modulator, attenuates scopolamine-induced quantitative electroencephalogram power spectral changes in cynomolgus monkeys, in the Journal: PLOS ONE | https://doi.org/10.1371/journal.pone [0207969]. March 11, 2019 of February/26,/2019
• what: The authors explored changes in quantitative electroencephalography (qEEG) power bands with or without scopolamine challenge as a non-invasive translational biomarker for the effect of TAK-071 in cynomolgus monkeys. To achieve high selectivity against M1R . . .
  

   

  

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