Tanshinone iia ameliorates aβ transendothelial transportation through sirt1-mediated endoplasmic reticulum stress

HIGHLIGHTS

  • who: Can Wan from the University of Chinese Medicine, Guangzhou, China have published the research: Tanshinone IIA ameliorates Au03b2 transendothelial transportation through SIRT1-mediated endoplasmic reticulum stress, in the Journal: (JOURNAL)
  • what: For the analysis of hippocampal CA2 and cortex regions, Image J was used to count the number of Nissl bodies, and GraphPad Prism was used for the statistical analysis.
  • how: Molecular docking and qPCR results showed that Tan mainly acted on Sirtuin1 (SIRT1) in Sirtuins famu2011 ily. The MTT result was shown that the maximum effect was achieved at 20 u00b5M . . .

     

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