Tanshinone iia improves acute gouty arthritis in rats through regulating neutrophil activation and the nlrp3 inflammasome

HIGHLIGHTS

  • who: Lianjie Xu and collaborators from the Faculty of Basic Medicine, Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan, China have published the Article: Tanshinone IIA Improves Acute Gouty Arthritis in Rats through Regulating Neutrophil Activation and the NLRP3 Inflammasome, in the Journal: Disease Markers of 19/Dec/2022
  • what: The authors aimed to elucidate the molecular mechanism of action of TIIA in the treatment of AGA in rat and cell models. The study showed that TIIA significantly enhanced IL-1RA expression and reduced IL-6, TNF-u03b1, IL8, CXCL1, CXCL2, S100A8A9, IL-1u03b2, and . . .

     

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