Tape-seq is a cell-based method for predicting genome-wide off-target effects of prime editor

HIGHLIGHTS

• who: Jeonghun Kwon from the Toolgen, Seoul, Republic of Korea have published the article: TAPE-seq is a cell-based method for predicting genome-wide off-target effects of prime editor, in the Journal: (JOURNAL) of 21/Dec/2022
• what: Although methods based on the analysis of Cas9 nuclease or nickase activity have been used to predict genome-wide off-target activities of PEs, no tool that directly uses PEs for this purpose has been reported yet. The authors present a cell-based assay, named TAgmentation of Prime Editor sequencing (TAPE-seq), that provides genome . . .
  

   

  

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