Target preference of type iii-a crispr-cas complexes at the transcription bubble

HIGHLIGHTS

• who: Tina Y. Liu from the University of California, Berkeley, CA, USA have published the research work: Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 29/01/2019
• what: The authors show that binding to a nascent RNA transcript tethers TthCsm to the TEC but does not trigger a direct interaction with RNAP or ssDNA in the transcription bubble.
• how: Particle picking for the complete dataset was carried out using Gautomatch (http// www.mrc-lmb.cam.ac.uk/kzhang/) with . . .
  

   

  

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