Targeted de novo phasing and long-range assembly by template mutagenesis

HIGHLIGHTS

• who: Targeted de novo phasing and colleagues from the Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA have published the paper: Targeted de novo phasing and long-range assembly by template mutagenesis, in the Journal: (JOURNAL) of January/06,/2022
• what: The authors demonstrate this method on a four-member nuclear family correctly assembling and three genomic intervals including the highly polymorphic HLA-B gene. The authors provide an overview of the method steps below and include details of the implementation in the Supplementary Methods. To illustrate this process, the authors explore the distribution . . .
  

   

  

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