Targeted delivery of irinotecan to colon cancer cells using epidermal growth factor receptor-conjugated liposomes

HIGHLIGHTS

  • who: Yongwei Liu from the Department of Infection, Chongqing, China (Southwest Hospital) have published the Article: Targeted delivery of irinotecan to colon cancer cells using epidermal growth factor receptor-conjugated liposomes, in the Journal: (JOURNAL)
  • what: The authors used the self-assembly method to investigate the effect of CPT-11-loaded DSPE-PEG2000 targeting EGFR liposome on the SW620 colon cancer cells.
  • how: The results indicated that the protein levels of cleaved-caspase-3 and cleaved-caspase-9 were considerably upregulated in cells treated with EGFR-Lipo-CPT-11 compared with that of . . .

     

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