HIGHLIGHTS
- who: Stefania C. Carrara and colleagues from the Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Alarich-Weiss-Strasse, Darmstadt, Germany have published the Article: Targeted Phagocytosis Induction for Cancer Immunotherapy via Bispecific MerTK-Engaging Antibodies, in the Journal: (JOURNAL) of 10/Dec/2022
SUMMARY
On macrophages, the most well-characterised signalling cascade is the phosphoinositide 3 kinase (PI3K)/AKT pathway, ultimately resulting in the phosphorylation of AKT (pAKT) through mediators in the signal_transduction and altered gene_expression. Macrophages are commonly known as the professional phagocytes of apoptotic cells (AC), as they . . .
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