HIGHLIGHTS
- who: Roy and Anirban from the DepartmentUniversity of Pharmacy, Houston, TX, USA have published the article: Targeted regulation of TAK1 counteracts dystrophinopathy in a DMD mouse, in the Journal: (JOURNAL)
- what: The authors have investigated how TAK1 affects the progression of dystrophic phenotype in the mdx mouse model of Duchenne muscular dystrophy (DMD). This analysis showed that TAK1 is expressed in regenerating myofibers as well as satellite cells (Fig 1G). Interestingly, the analysis showed that there was no difference in activation of various markers of these pathways in dystrophic muscle of mdx;Tak1fl/fl and . . .
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