Targeted therapy of b7 family checkpoints as an innovative approach to overcome cancer therapy resistance: a review from chemotherapy to immunotherapy

HIGHLIGHTS

  • who: Bita Amir Taghavi et al. from the Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran have published the research work: Targeted Therapy of B7 Family Checkpoints as an Innovative Approach to Overcome Cancer Therapy Resistance: A Review from Chemotherapy to Immunotherapy, in the Journal: Molecules 2022, 3545 of /2022/
  • how: In this study head and neck carcinoma cell lines were used to investigate the role of PD-L1 along with DNA repair complex (Mer11 Rad50 NBS1 MRN) in cisplatin-induced chemoresistance. That data showed that apoptosis was increased significantly in CA46 sh . . .

     

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