Targeting 4-1bb and pd-l1 induces potent and durable antitumor immunity in b-cell lymphoma

HIGHLIGHTS

• who: Yichen Wang from the European Institute of Oncology (IEO), Italy Duke University, United States have published the Article: Targeting 4-1BB and PD-L1 induces potent and durable antitumor immunity in B-cell lymphoma, in the Journal: (JOURNAL)
• what: The research showed that anti-PD-L1 mAb in combination with low dose of 4-1BB agonistic Ab (1 mg/kg) elicited synergistic antitumor activity with no obvious toxicity, whereas PD-L1 blockade or 4-1BB agonism alone only had modest antitumor effects.
• how: The results showed that combining anti-PD-L1 ICI . . .
  

   

  

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