Targeting abcc6 in mesenchymal stem cells: impairment of mature adipocyte lipid homeostasis

HIGHLIGHTS

• who: Ricarda Plümers et al. from the Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen, Germany have published the article: Targeting ABCC6 in Mesenchymal Stem Cells: Impairment of Mature Adipocyte Lipid Homeostasis, in the Journal: (JOURNAL)
• what: The intention of this study was to examine the influence of ABCC6 deficiency during adipogenic differentiation of human bone marrow-derived stem cells (hMSCs). In the next step, the authors intended to establish a clustered regulatory interspaced short palindromic repeat (CRISPR-Cas9) system to deplete ABCC6 in hMSCs, followed by the analysis of lipid homeostasis in . . .
  

   

  

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