Targeting annexin a7 by a small molecule suppressed the activity of phosphatidylcholine-specific phospholipase c in vascular endothelial cells and inhibited atherosclerosis in apolipoprotein e−/− mice

HIGHLIGHTS

• who: H Li from the Institut Shandong University, Jinan, China have published the Article: Targeting annexin A7 by a small molecule suppressed the activity of phosphatidylcholine-specific phospholipase C in vascular endothelial cells and inhibited atherosclerosis in apolipoprotein E−/− mice, in the Journal: (JOURNAL)
• what: The authors identified the antiatherosclerotic role of ANXA7 for the first time, and compared with genetic modulation, ABO may be a powerful and ideal regulator of ANXA7 for atherosclerosis treatment.
• how: The results showed that the number of LC3 puncta was significantly increased by ABO treatment suggesting . . .
  

   

  

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