Targeting camkk2 and soc channels as a novel therapeutic approach for sensitizing acute promyelocytic leukemia cells to all-trans retinoic acid

HIGHLIGHTS

• who: Faten Merhi et al. from the Institut Bergoniu00e9, INSERM, University of Bordeaux, Bordeaux, France have published the research work: Targeting CAMKK2 and SOC Channels as a Novel Therapeutic Approach for Sensitizing Acute Promyelocytic Leukemia Cells to All-Trans Retinoic Acid, in the Journal: Cells 2021, 10, 3364. of /2021/
• what: The authors report the activation of both SOC-dependent 14 of 19 The authors propose that inhibiting CAMMK2 and SOC-channels may constitute a novel approach to increasing the efficacy of ATRA against APL.
• how: The data are in line with earlier . . .
  

   

  

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