Targeting class i histone deacetylases in human uterine leiomyosarcoma

HIGHLIGHTS

  • who: Qiwei Yang and colleagues from the Department of Obstetrics and Gynecology, University of Chicago, Chicago, IL, USA have published the research work: Targeting Class I Histone Deacetylases in Human Uterine Leiomyosarcoma, in the Journal: Cells 2022, 3801 of 27/Oct/2021
  • what: The authors assessed the expression panel of HDACs in uLMS and characterized the role and mechanism of HDACs in the pathogenesis of uLMS. The studies demonstrated that Tucidinostat gene-expression program in cancer cells . The studies demonstrated that Tucidinostat andDL-sulforaphane DL-sulforaphane inducedDEGs are putative of multiple transcriptional and inducedDEGs are . . .

     

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