HIGHLIGHTS
- who: Yang Meng from the Care of Laboratory AnimalsAll protocols used in this study were approved by the Institutional Animal Care and Treatment Committee of Sichuan University in China. (Approval No., ). have published the Article: Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy, in the Journal: (JOURNAL) of 11/Nov/2022
- what: The authors showed that irregular expression of CRL4CUL4A/DDB1 facilitated mitochondrial dysfunction, including decreased mitochondrial membrane potential, decreased ATP synthesis, and diminished oxygen consumption rate of mitochondria in cisplatin-resistant OCCs.
- how: Cullin4 E3 ubiquitin ligase has been reported . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.