Targeting dna repair, cell cycle, and tumor microenvironment in b cell lymphoma

HIGHLIGHTS

  • who: Paul J. Bröckelmann et al. from the Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO, University of Cologne, Cologne, Germany have published the research: Targeting DNA Repair, Cell Cycle, and Tumor Microenvironment in B Cell Lymphoma, in the Journal: (JOURNAL)
  • what: Lastly the authors provide a clinical perspective by highlighting treatment possibilities of defective DDR signaling and the TME in mantle cell lymphoma which serves as a blueprint for B cell lymphomas.
  • how: Similar observations were made in syngeneic mouse models and samples derived from . . .

     

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