Targeting epigenetic features in clear cell sarcomas based on patient-derived cell lines

HIGHLIGHTS

• who: Christina Karner from the A, year-old woman was diagnosed with a CCS invading her left knee joint in December A biopsy revealed a CCS involving the EWSR1::ATF1-fusion gene. In January, extra articular left knee resection was subsequently performed by the Department of Orthopedics and Trauma at the Medical University of Graz. Tumor tissue obtained from this surgery was used to establish MUG Lucifer prim and a piece of skin served to isolate non-tumorigenic control cells. In October, the patient developed large soft tissue and lymph node metastases in the left groin and . . .
  

   

  

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