Targeting erβ to fight melanoma: a new valid approach?

HIGHLIGHTS

  • who: Marzia Di Donato from the (UNIVERSITY) have published the article: Targeting ERu03b2 to fight melanoma: a new valid approach?, in the Journal: (JOURNAL)
  • future: The paper recently published by Bechmann et_al reports that ERu03b2 gene_expression does not change with melanoma progression while sustained ERu03b1 gene_expression correlates with extension of OS in a retrospective study from 448 patients. The subsequent discovery that an orphan GPCR (GPR30 then renamed GPER) is required for rapid estrogen signaling opened new perspectives in estrogen biology and hormone-dependent cancers .

SUMMARY

    Journal of Translational Medicine Open . . .

     

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