Targeting herpes simplex virus-1 gd by a dna aptamer can be an effective new strategy to curb viral infection

HIGHLIGHTS

  • who: Tejabhiram Yadavalli from the University of Technology (AIST), Tsukuba Science City, Ibaraki, Japan have published the research work: Targeting Herpes Simplex Virus-1 gD by a DNA Aptamer Can Be an Effective New Strategy to Curb Viral Infection, in the Journal: (JOURNAL)
  • what: The authors demonstrate that HSV-1 envelope glycoprotein which is essential for viral entry and spread can be specifically targeted by topical applications of a small DNA aptamer to effectively control ocular infection by the the 45 -nt-long DNA aptamer showed high affinity for HSV-1 (binding affinity constant = 50 . . .

     

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