Targeting hif-1 by natural and synthetic compounds: a promising approach for anti-cancer therapeutics development

HIGHLIGHTS

  • who: Rituparna Ghosh et al. from the Department of Chemoprevention, Chittaranjan National Institute (CNCI), Kolkata, India have published the article: Targeting HIF-1 by Natural and Synthetic Compounds: A Promising Approach for Anti-Cancer Therapeutics Development, in the Journal: Molecules 2022, 27, 5192. of /2022/
  • what: In this review the authors provide brief descriptions of natural and synthetic compounds as HIF-1α inhibitors that have the potential to accelerate anticancer drug discovery. Along with these, the authors focus on some other synthetic chemotherapeutic drugs which inhibit HIF-1α directly by interfering its binding to DNA . . .

     

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