Targeting hiv-1 reverse transcriptase using a fragment-based approach

HIGHLIGHTS

• who: Mahta Mansouri et al. from the Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia have published the Article: Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach, in the Journal: Molecules 2023, 28, x FOR PEER REVIEW of 28/Dec/2022
• what: The aim of this work was to follow a systematic fragment development process to elaborate the promising hit compound B-1 in an effort to target the NNRTI Adjacent site. The authors aimed to optimize the binding and HIV-1 RT inhibitory activity of ofcompound novel inhibitors targeting thisRT . . .
  

   

  

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