HIGHLIGHTS
- who: Alexis Hofherr from the (UNIVERSITY) have published the article: Targeting inflammation for the treatment of Diabetic Kidney Disease: a five-compartment mechanistic model, in the Journal: (JOURNAL)
- what: The authors show how the model can help to align pre-clinical models for target validation with clinical efficacy endpoints and patient selection criteria.
- future: As discussed in the section on clinical trial design this approach would currently require kidney biopsy but may in future be based on circulatory urinary or imaging biomarkers .
SUMMARY
With type 2 diabetes, with around . . .
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