Targeting mechano-transcription process as therapeutic intervention in gastrointestinal disorders

HIGHLIGHTS

  • who: Targeting Mechano-Transcription and collaborators from the Department of Internal Medicine, The University of Texas Medical Branch, Galveston, TX, United States have published the research work: Targeting Mechano-Transcription Process as Therapeutic Intervention in Gastrointestinal Disorders, in the Journal: (JOURNAL)
  • what: This work shows that mechanical stress substantially alters the gene_expression profile in the gut. The studies have revealed that smooth muscle contractility of the isolated circular muscle strips was suppressed dramatically at 24 h after obstruction, which continued through the 7-days course of obstruction (Shi et_al, 2011; Li et_al, 2012a). Abdominal pain . . .

     

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