Targeting mir-18a sensitizes chondrocytes to anticytokine therapy to prevent osteoarthritis progression

HIGHLIGHTS

• who: Chengjie Lian from the Human cartilage samples were obtained from , OA patients (, women and , men with a mean age of (, ±, .90) years) classified as grades , and , according to the Kellgren and Lawrence osteoarthritis grading system. The patients underwent total knee arthroplasty at the First Affiliated Hospital of Chongqing Medical University from , to, . Cartilage samples were taken from both the injured area (mostly from the rim of the ulcer, comprising ~3, mm of the surrounding tissue) and the macroscopically unaffected area distal to the damaged zone. Measurements of mRNA and miRNA expressions and histology were performed. The . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.