Targeting myeloid cell coagulation signaling blocks map kinase/tgf-β1-driven fibrotic remodeling in ischemic heart failure

HIGHLIGHTS

• who: Venkata Garlapati et al. from the Center for ThrombosisUniversity Medical Center Mainz, Mainz, Germany have published the research: Targeting myeloid cell coagulation signaling blocks MAP kinase/TGF-u03b21-driven fibrotic remodeling in ischemic heart failure, in the Journal: (JOURNAL)
• what: The authors identified persistent activation of coagulation as a prominent local feature in human IHF. In a sample taken from the observational MICAT study, the authors focused on patients with subacute MI compared with stable coronary artery disease (CAD) admitted for percutaneous coronary intervention (PCI) (Supplemental Table 5). The authors provide novel insights into . . .
  

   

  

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