HIGHLIGHTS
- who: Yi-Chao Zheng from the (UNIVERSITY) have published the research: Targeting neddylation E2s: a novel therapeutic strategy in cancer, in the Journal: (JOURNAL)
- what: This review discusses the current knowledge on the neddylation E2 enzymes UBE2M and UBE2F, including their structures, binding partners, substrates, and roles in the diverse biological processes.
- how: This review discusses the structure of neddylationrelated E2 enzymes and summarizes the current understanding of their mechanism and effect in biological processes.
SUMMARY
Pathway causes an increase in the levels of tumor-promoting factors and a . . .
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