Targeting of epigenetic co-dependencies enhances anti-aml efficacy of menin inhibitor in aml with mll1-r or mutant npm1

HIGHLIGHTS

• who: Warren Fiskus from the Primary AML blasts Patient-derived AML cells samples were obtained with informed consent as part of a clinical protocol approved by the Institutional Review Board of The University of Texas, MD. Anderson Cancer Center. Mononuclear cells were purified by Ficoll Hypaque (Axis Shield, Oslo, Norway) density centrifugation following the manufacturer`s protocol. Mononuclear cells were washed once with sterile, u00d7 PBS then suspended in complete RPMI media containing, % FBS. have published the article: Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant . . .
  

   

  

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