Targeting of phagolysosomes containing conidia of the fungus

HIGHLIGHTS

  • who: Katherine Gonzu00e1lez from the (UNIVERSITY) have published the paper: Targeting of phagolysosomes containing conidia of the fungus, in the Journal: (JOURNAL)
  • what: The authors demonstrate that PPs can reach conidia-containing phagolysosomes making these particles a promising carrier system for antimicrobial drugs to target intracellular pathogens. The authors report the formulation of fluorescent-labeled PLGA microparticles with a size of approximately 800 nm to enable their phagocytosis and intracellular processing in macrophages. The major aim of this study was targeting intracellularly persisting pathogenic microorganisms with PPs.
  • how: To determine the uptake of . . .

     

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