HIGHLIGHTS
- who: Gaofu Li et al. from the Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, China School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China have published the article: Targeting OPA1-Mediated Mitochondrial Fusion Contributed to Celastrolu2019s Anti-Tumor Angiogenesis Effect, in the Journal: Pharmaceutics 2023, 48 of /2023/
- what: This study shows that celastrol exerts visible suppression on growth and in a cell-derived xenograft (CDX). The authors show that celastrol can significantly inhibit angiogenesis inside the solid tumor, at the same time, the mitochondrial length of HUVECs is dramatically decreased. The downregulation . . .
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