Targeting polarized phenotype of microglia via il6/jak2/stat3 signaling to reduce nsclc brain metastasis

HIGHLIGHTS

• who: Yu Jin from the Cell culture and reagents NSCLC cell lines (A549, , and, ) were obtained from the Oncology Laboratory of Tongji Hospital (Wuhan, China) and cultured in , (Hyclone, Provo, UT) supplemented with, % fetal bovine serum (FBS have published the Article: Targeting polarized phenotype of microglia via IL6/JAK2/STAT3 signaling to reduce NSCLC brain metastasis, in the Journal: (JOURNAL) of 29/Dec/2021
• what: This work investigated NSCLC metastatic cell colonization of the brain, focusing on the MET. The study showed that brain-specific metastatic A549-F3 cells induced M2 microglia via the IL6 . . .
  

   

  

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