Targeting proteotoxic stress in cancer: a review of the role that protein quality control pathways play in oncogenesis

HIGHLIGHTS

  • who: Matthew Ho Zhi Guang and collaborators from the UCD Conway Institute of Biomolecular and Biomedical Science, Dublin, Dublin, IrelandUCD School of Medicine, College of Health and Agricultural Sciences, University College Dublin have published the research work: Targeting Proteotoxic Stress in Cancer: A Review of the Role that Protein Quality Control Pathways Play in Oncogenesis, in the Journal: (JOURNAL)
  • what: The authors provide new insights gleaned from the use of emerging technologies to disrupt the protein secretory pathway and repurpose E3 ligases to achieve targeted protein degradation.
  • how: In this study a pool . . .

     

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