Targeting pulmonary vascular endothelial cells for the treatment of respiratory diseases

HIGHLIGHTS

• who: August et al. from the University of Illinois at Chicago, United States have published the research: Targeting pulmonary vascular endothelial cells for the treatment of respiratory diseases, in the Journal: (JOURNAL)
• what: This study provided the basis for the development of targeted delivery systems for mRNA therapy in lung diseases, including acute lung injury, pulmonary hypertension, etc.
• how: The results showed that anti-PECAM scFv/TM M388L had good endothelial targeting property and anti-thrombotic activity of TM under oxidative stress (Carnemolla et_al 2013). The results showed that flow modulates endothelial endocytosis . . .
  

   

  

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