Targeting rna g-quadruplex with repurposed drugs blocks sars-cov-2 entry

HIGHLIGHTS

  • who: Qiyu Tong et al. from the Laboratory of Biotherapy and Cancer Center, West China, University and Collaborative have published the article: Targeting RNA G-quadruplex with repurposed drugs blocks SARS-CoV-2 entry, in the Journal: (JOURNAL) of January/26,/2023
  • what: The authors report the potential of RNA G-quadruplex (RG4)-targeting therapeutic strategy for SARS-CoV-2 entry. Combining bioinformatics biochemical and biophysical approaches the authors characterize the existence of RG4s in several SARS-CoV-2 host factors. Given that drug repurposing has been extensively used to meet the unmet need for . . .

     

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