Targeting the androgen receptor to enhance nk cell killing efficacy in bladder cancer by modulating adar2/circ_0001005/pd-l1 signaling

HIGHLIGHTS

• who: Qing Liu from the In vivo studies For in vivo studies, male, athymic BALB/c nude mice (, weeks old) were randomly distributed into four groups (n=, per group)TCC-SUP cells with or without , cells with Effector cells: Target cells ratio=1:, (E.T. ratio=1.5) were injected subcutaneously to establish the xenograft model. Two weeks after implantation, when the tumors were observed, mice were intraperitoneally treated with , mg/kg Enz or DMSO every other day for , weeks until mice met treatment endpoints. The average gross tumor sizes of each group were monitored during the . . .
  

   

  

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