Targeting the bacterial cytoskeleton of the burkholderia cepacia complex for antimicrobial development: a cautionary tale

HIGHLIGHTS

  • who: Sonya C. Carnell and colleagues from the Institute of Cellular Medicine, Newcastle University, Newcastle , HH, UK have published the Article: Targeting the Bacterial Cytoskeleton of the Burkholderia cepacia Complex for Antimicrobial Development: A Cautionary Tale, in the Journal: (JOURNAL)
  • what: The authors demonstrate that the novel compound Q22 which is related to the bacterial cytoskeleton destabilising compound A22 can reduce the growth rate and inhibit growth of BCC bacteria. The authors show that sub-lethal treatment of BCC with Q22 altered virulence phenotypes, including increased resistance to oxidative stress and pro-inflammatory potential, suggesting . . .

     

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